Article
[The significance of quantification of MDR1 and WT1 gene expression in acute myeloid leukemia].
Zhonghua nei ke za zhi - 1 Mar 2008
Xu Bing, Song Xiao-Yan, Li Lin, Xu Wen-Juan, Tang Jia-Hong
Abstract excerpt
OBJECTIVE: To study the quantification of MDR1 and WT1 gene expression in patients with de novo acute myeloid leukemia (AML) and to explore the role of these two genes in clinical drug resistance and their correlation with risk stratification. METHODS: A real time quantitative reverse transcriptase polymerase chain reaction method was established for detecting MDR1 and WT1 gene expression levels in 63 de novo AML...
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