Article
Prognostic significance of WT1 expression at diagnosis and end of induction in Egyptian adult acute myeloid leukemia patients.
Hematology (Amsterdam, Netherlands) - 1 Mar 2013
Mossallam Ghada I, Abdel Hamid Thoraya M, Mahmoud Hossam K
Abstract excerpt
BACKGROUND: Wilms' tumor (WT1) gene overexpression has been reported in the majority of acute myeloid leukemia (AML) patients at diagnosis and has been evaluated as prognostic and minimal residual disease (MRD) marker. PATIENTS AND METHODS: WT1 overexpression was evaluated in 68 adult AML patients at diagnosis and at the end of induction using quantitative real-time polymerase chain reaction (PCR). RESULTS: No...
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