Article
Androgen receptor CAG repeat polymorphisms in canine prostate cancer.
Journal of veterinary internal medicine - 1 Jan 2000
Lai C-L, L'Eplattenier H, van den Ham R, Verseijden F, Jagtenberg A, Mol J A, Teske E
Abstract excerpt
BACKGROUND: Relatively shorter lengths of the polymorphic polyglutamine repeat-1 of the androgen receptor (AR) have been associated with an increased risk of prostate cancer (PC) in humans. In the dog, there are 2 polymorphic CAG repeat (CAGr) regions. OBJECTIVE: To investigate the relationship of CAGr length of the canine AR-gene and the development of PC. ANIMALS: Thirty-two dogs with PC and 172 control dogs...
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