Article
Polymorphic CAG and GGC repeat lengths in the androgen receptor gene and prostate cancer risk: analysis of a Brazilian population.
Cancer investigation - 1 Feb 2008
Silva Neto Brasil, Koff Walter J, Biolchi Vanderlei, Brenner Cleber, Biolo Karlo D, Spritzer Poli Mara, Brum Ilma S
Abstract excerpt
Variations in transcriptional activity of the androgen receptor (AR) are related to polymorphic CAG and GGC repeats in exon 1 of the AR gene. We investigated the association between CAG and GGC repeat length and the risk of prostate cancer in a case-control study from a Brazilian population. We evaluated 49 patients and 51 healthy controls. DNA was extracted from peripheral leukocytes and the AR gene was analyzed...
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