A large study of androgen receptor germline variants and their relation to sex hormone levels and prostate cancer risk. Results from the National Cancer Institute Breast and Prostate Cancer Cohort Consortium.

doi:10.1210/jc.2009-1911

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Article

A large study of androgen receptor germline variants and their relation to sex hormone levels and prostate cancer risk. Results from the National Cancer Institute Breast and Prostate Cancer Cohort Consortium.

The Journal of clinical endocrinology and metabolism - 1 Sept 2010

Lindström Sara, Ma Jing, Altshuler David, Giovannucci Edward, Riboli Elio, Albanes Demetrius, Allen Naomi E, Berndt Sonja I, Boeing Heiner, Bueno-de-Mesquita H Bas, Chanock Stephen J, Dunning Alison M, Feigelson Heather Spencer, Gaziano J Michael, Haiman Christopher A, Hayes Richard B, Henderson Brian E, Hunter David J, Kaaks Rudolf, Kolonel Laurence N, Le Marchand Loic, Martínez Carmen, Overvad Kim, Siddiq Afshan, Stampfer Meir, Stattin Pär, Stram Daniel O, Thun Michael J, Trichopoulos Dimitrios, Tumino Rosario, Virtamo Jarmo, Weinstein Stephanie J, Yeager Meredith, Kraft Peter, Freedman Matthew L

Abstract excerpt

BACKGROUND: Androgens are key regulators of prostate gland maintenance and prostate cancer growth, and androgen deprivation therapy has been the mainstay of treatment for advanced prostate cancer for many years. A long-standing hypothesis has been that inherited variation in the androgen receptor...

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Identifiers

PMID: 20534771
DOI: 10.1210/jc.2009-1911
PMCID: PMC2936075

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20534771-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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