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Article

Effect of HLA genotype or CTLA-4 polymorphism on cytokine response in healthy children.

Scandinavian journal of immunology - 1 Sept 2008

Walldén J, Ilonen J, Roivainen M, Ludvigsson J, Vaarala O

Abstract excerpt

Type 1 diabetes (T1D) is considered to be a T-cell-mediated autoimmune disease in which genetic predisposition is affected by HLA class II alleles and polymorphisms in cytotoxic T-lymphocyte-associated antigen-4 (CTLA-4) gene. We tested the hypothesis whether these T1D-related gene polymorphisms modulate cytokine response and thus contribute to the development of autoimmunity. The study includes 67 non-diabetic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18782261
DOI: 10.1111/j.1365-3083.2008.02144.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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