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Article

Patients with early onset of type 1 diabetes have significantly higher GG genotype at position 49 of the CTLA4 gene.

Human immunology - 1 Jul 2004

Zalloua Pierre A, Abchee Antoine, Shbaklo Hadia, Zreik Tony G, Terwedow Henry, Halaby Georges, Azar Sami T

Abstract excerpt

Type 1 diabetes (T1D) is a complex autoimmune disease. Several genetic loci have been implicated in the susceptibility to this illness. Evaluated was the role of the CTLA4 exon 1 A49G polymorphism and its role as a risk factor for T1D in our population. DNA from 190 patients with T1D and their families and 96 control individuals were genotyped for CTLA4 exon 1 polymorphism and human leukocyte antigen...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15301861
DOI: 10.1016/j.humimm.2004.04.007

Genes

CTLA4

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Patients with early onset of type 1 diabetes have significantly higher GG genotype at position 49 of the CTLA4 gene.PMID 15301861Read ↗

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