Article
Combined polymorphism analysis of glutathione S-transferase M1/G1 and interleukin-1B (IL-1B)/interleukin 1-receptor antagonist (IL-1RN) and gastric cancer risk in an Omani Arab Population.
Journal of clinical gastroenterology - 1 Feb 2009
Al-Moundhri Mansour S, Alkindy Mohamed, Al-Nabhani Maryam, Al-Bahrani Bassim, Burney Ikram A, Al-Habsi Hamdan, Ganguly Shyam S, Tanira Musbah
Abstract excerpt
BACKGROUND: Host genetics have been implicated in gastric cancer carcinogenesis. Polymorphisms of glutathione S-transferase (GST) M1 and G1 and of interleukin-1B (IL-1B) and interleukin-1 receptor antagonist (IL-1RN) were shown to increase gastric cancer predisposition in several studies. To our knowledge, this is the first report on the combined analysis of polymorphisms GSTM1/G1 and IL-1B/IL-1RN genes in...
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