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Article

The impact of evolutionary constraints on influenza dynamics.

Vaccine - 18 Jul 2008

Gog Julia R

Abstract excerpt

Existing mathematical models of drift typically assume that influenza A is free to change its antigenic properties without any fitness cost in other respects. This paper asks what might be the impact of antigenic mutations being bound to fitness cost. The effect on drift is explored via a mathematical model. This paper also offers some novel features for multi-strain modeling. In contrast to the unconstrained...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18773528
DOI: 10.1016/j.vaccine.2008.04.008

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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