Article
Dynamics and selection of many-strain pathogens.
Proceedings of the National Academy of Sciences of the United States of America - 24 Dec 2002
Gog Julia R, Grenfell Bryan T
Abstract excerpt
Strain structure is of fundamental importance in the underlying dynamics of a number of pathogens. However, previous models have been too complex to accommodate many strains. This paper offers a solution to this problem, in the form of a simple model that is capable of capturing the dynamics of a large number of antigenic types that interact via host cross-immunity. We derive the structure of the model, which can...
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