Article
Modelling heterogeneous host immune response in a multi-strain system.
Journal of theoretical biology - 7 Jul 2012
Simpson Joanne, Roberts Mick
Abstract excerpt
We explore the dynamics that occur when multiple variants of a virus are released in a population, where hosts can make an immune response to only one epitope of the virus. A heterogeneous immune response was implemented by varying the probability for making a response at a locus of the virus variants. A framework based on an SIR model is presented which allows for the explicit representation of the virus...
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