Article
IFATS collection: Fibroblast growth factor-2-induced hepatocyte growth factor secretion by adipose-derived stromal cells inhibits postinjury fibrogenesis through a c-Jun N-terminal kinase-dependent mechanism.
Stem cells (Dayton, Ohio) - 1 Jan 2009
Suga Hirotaka, Eto Hitomi, Shigeura Tomokuni, Inoue Keita, Aoi Noriyuki, Kato Harunosuke, Nishimura Satoshi, Manabe Ichiro, Gonda Koichi, Yoshimura Kotaro
Abstract excerpt
Adipose-derived stem/stromal cells (ASCs) not only function as tissue-specific progenitor cells but also are multipotent and secrete angiogenic growth factors, such as hepatocyte growth factor (HGF), under certain circumstances. However, the biological role and regulatory mechanism of this secretion have not been well studied. We focused on the role of ASCs in the process of adipose tissue injury and repair and...
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