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Article

Inhibition and reversal of a TGF-β1 induced myofibroblast phenotype by adipose tissue-derived paracrine factors.

Stem cell research & therapy - 13 Jun 2024

Higginbotham S, Workman V L, Giblin A-V, Green N H, Lambert D W, Hearnden V

Abstract excerpt

BACKGROUND: Hypertrophic scarring results from myofibroblast differentiation and persistence during wound healing. Currently no effective treatment for hypertrophic scarring exists however, autologous fat grafting has been shown to improve scar elasticity, appearance, and function. The aim of this study was to understand how paracrine factors from adipose tissues and adipose-derived stromal cells (ADSC) affect...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 38867276
DOI: 10.1186/s13287-024-03776-3
PMCID: PMC11170827

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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