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Article

IFATS collection: Adipose stromal cells adopt a proangiogenic phenotype under the influence of hypoxia.

Stem cells (Dayton, Ohio) - 1 Jan 2009

Thangarajah Hariharan, Vial Ivan N, Chang Edwin, El-Ftesi Samyra, Januszyk Michael, Chang Edward I, Paterno Josemaria, Neofytou Evgenios, Longaker Michael T, Gurtner Geoffrey C

Abstract excerpt

Evolving evidence suggests a possible role for adipose stromal cells (ASCs) in adult neovascularization, although the specific cues that stimulate their angiogenic behavior are poorly understood. We evaluated the effect of hypoxia, a central mediator of new blood vessel development within ischemic tissue, on proneovascular ASC functions. Murine ASCs were exposed to normoxia (21% oxygen) or hypoxia (5%, 1% oxygen)...

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Share to Adipose Tissue
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chemokine CXCL12

Share to Endothelial Cells

Share to Hypoxia-Inducible Factor 1, alpha Subunit

Share to Neovascularization, Physiologic

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Source

Identifiers

PMID: 18974212
DOI: 10.1634/stemcells.2008-0276

Genes

CXCR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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