Article
Fibroblast growth factor and vascular endothelial growth factor play a critical role in endotheliogenesis from human adipose-derived stem cells.
Journal of vascular surgery - 1 May 2017
Khan Sophia, Villalobos Miguel A, Choron Rachel L, Chang Shaohua, Brown Spencer A, Carpenter Jeffrey P, Tulenko Thomas N, Zhang Ping
Abstract excerpt
OBJECTIVE: Adipose-derived stem cells (ASCs) are a potential adult mesenchymal stem cell source for restoring endothelial function in patients with critical limb ischemia. Fibroblast growth factor 2 (FGF2) and vascular endothelial growth factor (VEGF) play a major role in angiogenesis and wound healing. This study evaluated the effects of FGF and VEGF on the proliferation, migration, and potential endothelial...
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