Article
Study of cytochrome P450 2E1 and its allele variants in liver injury of nondiabetic, nonalcoholic steatohepatitis obese women.
Biological research - 1 Jan 2008
Varela Nelson M, Quiñones Luis A, Orellana Myriam, Poniachik Jaime, Csendes Attila, Smok Gladys, Rodrigo Ramón, Cáceres Dante D, Videla Luis A
Abstract excerpt
CYP2E1 enzyme is related to nonalcoholic steatohepatitis (NASH) due to its ability for reactive oxygen species production, which can be influenced by polymorphisms in the gene. The aim of this study was to investigate hepatic levels, activity, and polymorphisms of the CYP2E1 gene to correlate it...
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