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Article

Enhancement of tumor-TRAIL susceptibility by modulation of autophagy

25 Aug 2008

Abstract excerpt

Autophagy has recently been recognized as an important cellular response to stress. However, the prospect of manipulating the autophagic process for the enhancement of cancer therapy remains unresolved. This lack of resolution stems from the current controversy regarding the fundamental function of autophagy in tumor stress response: Does it have a positive or negative impact on tumor survival capability? Our...

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PMID: 18769107
DOI: 10.4161/auto.6769

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