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Influences of Reduced Expression of Maternal Bone Morphogenetic Protein 2 on Mouse Embryonic Development

1 Jan 2008

Abstract excerpt

Bone morphogenetic protein 2 (BMP2) was originally found by its osteoinductive ability, and recent genetic analyses have revealed that it plays critical roles during early embryogenesis, cardiogenesis, decidualization as well as skeletogenesis. In the course of evaluation of the conditional allele for Bmp2, we found that the presence of a neo cassette, a selection marker needed for gene targeting events in...

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PMID: 18769073
DOI: 10.1159/000143431

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