Article
Fibroblast growth factor-regulated palmitoylation of the neural cell adhesion molecule determines neuronal morphogenesis.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 3 Sept 2008
Ponimaskin Evgeni, Dityateva Galina, Ruonala Mika O, Fukata Masaki, Fukata Yuko, Kobe Fritz, Wouters Fred S, Delling Markus, Bredt David S, Schachner Melitta, Dityatev Alexander
Abstract excerpt
During development of the nervous system, short- and long-range signals cooperate to promote axonal growth, guidance, and target innervation. Particularly, a short-range signal transducer, the neural cell adhesion molecule (NCAM), stimulates neurite outgrowth via mechanisms that require posttranslational modification of NCAM and signaling via receptors to a long-range messenger, the fibroblast growth factor...
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