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Article

Association of polymorphisms in cyclooxygenase (COX)-2 with coronary and carotid calcium in the Diabetes Heart Study.

Atherosclerosis - 1 Apr 2009

Rudock Megan E, Liu Yongmei, Ziegler Julie T, Allen Stewart G, Lehtinen Allison B, Freedman Barry I, Carr J Jeffrey, Langefeld Carl D, Bowden Donald W

Abstract excerpt

BACKGROUND: Cardiovascular disease is the leading cause of death among Americans. Inflammation is a hallmark of the development of atherosclerosis and is mediated by prostaglandins, catalyzed by cyclooxygenase (COX)-2. We sought to determine if variants in the COX-2 gene were associated with subclinical measures of cardiovascular disease in a primarily type 2 diabetic population. METHODS: Eight polymorphisms in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 18768181
DOI: 10.1016/j.atherosclerosis.2008.07.018
PMCID: PMC2699582

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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