Article
Coronary artery calcification and its relationship to validated genetic variants for diabetes mellitus assessed in the Heinz Nixdorf recall cohort.
Arteriosclerosis, thrombosis, and vascular biology - 1 Sept 2010
Pechlivanis Sonali, Scherag André, Mühleisen Thomas W, Möhlenkamp Stefan, Horsthemke Bernhard, Boes Tanja, Bröcker-Preuss Martina, Mann Klaus, Erbel Raimund, Jöckel Karl-Heinz, Nöthen Markus M, Moebus Susanne
Abstract excerpt
OBJECTIVE: To examine the association between genomewide association study-based diabetes mellitus-related single-nucleotide polymorphisms (SNPs) and coronary artery calcification (CAC), a valid risk factor for coronary heart disease, in a large, unselected, population-based cohort. METHODS AND RESULTS: We genotyped 11 validated genomewide association study-based diabetes SNPs in 4459 participants of the Heinz...
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