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Article

Association of protein tyrosine phosphatase-N1 polymorphisms with coronary calcified plaque in the Diabetes Heart Study.

Diabetes - 1 Mar 2006

Burdon Kathryn P, Bento Jennifer L, Langefeld Carl D, Campbell Joel K, Carr J Jeffery, Wagenknecht Lynne M, Herrington David M, Freedman Barry I, Rich Stephen S, Bowden Donald W

Abstract excerpt

Individuals with type 2 diabetes are at increased risk of cardiovascular disease (CVD) mortality and display increased levels of subclinical CVD. Genetic variation in PTPN1, a diabetes susceptibility gene, was investigated for a role in diabetic atherosclerosis. The PTPN1 gene encodes protein tyrosine phosphatase-1B, which is ubiquitously expressed and plays a role in the regulation of several signaling pathways....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16505227
DOI: 10.2337/diabetes.55.03.06.db05-0058

Genes

PTPN1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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