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Article

Association of RNASEL variants with prostate cancer risk in Hispanic Caucasians and African Americans.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Oct 2007

Shook Stacie J, Beuten Joke, Torkko Kathleen C, Johnson-Pais Teresa L, Troyer Dean A, Thompson Ian M, Leach Robin J

Abstract excerpt

PURPOSE: The RNASEL gene at 1q25 has been identified as a hereditary prostate cancer susceptibility gene, but to date, no study has investigated the role of RNASEL variants in Hispanic Caucasian men with prostate cancer. EXPERIMENTAL DESIGN: Two RNASEL common variants, located at amino acids 462 and 541, were genotyped in non-Hispanic Caucasian, Hispanic Caucasian, and African American prostate cancer cases and...

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Source

Identifiers

PMID: 17908993
DOI: 10.1158/1078-0432.CCR-07-0702

Genes

RNASEL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Association of RNASEL variants with prostate cancer risk in Hispanic Caucasians and African Americans.PMID 17908993Read ↗

RNASEL gene polymorphisms and the risk of prostate cancer: a meta-analysis.Semantic proximity Read ↗

Association of HPC2/ELAC2 and RNASEL non-synonymous variants with prostate cancer risk in African American familial and sporadic cases.Semantic proximity Read ↗

Genetic variation in RNASEL and risk for prostate cancer in a population-based case-control study.Semantic proximity Read ↗

Evidence from 40 Studies that 2 Common Single-Nucleotide Polymorphisms (SNPs) of RNASEL Gene Affect Prostate Cancer Susceptibility: A Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA)-Compliant Meta-Analysis.Semantic proximity Read ↗

Association of RNASEL and 8q24 variants with the presence and aggressiveness of hereditary and sporadic prostate cancer in a Hispanic population.Semantic proximity Read ↗

Single and multivariate associations of MSR1, ELAC2, and RNASEL with prostate cancer in an ethnic diverse cohort of men.Semantic proximity Read ↗

Association of hereditary prostate cancer gene polymorphic variants with sporadic aggressive prostate carcinoma.Semantic proximity Read ↗

RNASEL Arg462Gln variant is implicated in up to 13% of prostate cancer cases.Semantic proximity Read ↗

Germline Alterations of the RNASEL Gene, a Candidate HPC1 Gene at 1q25, in Patients and Families with Prostate CancerSemantic proximity Read ↗

Association of susceptibility alleles in ELAC2/HPC2, RNASEL/HPC1, and MSR1 with prostate cancer severity in European American and African American men.Semantic proximity Read ↗

RNASEL and RNASEL-inhibitor variation and prostate cancer risk in Afro-Caribbeans.Semantic proximity Read ↗

Role of genetic polymorphisms of the RNASEL gene on familial prostate cancer risk in a Japanese population.Semantic proximity Read ↗

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