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Article

Calcineurin-dependent lytic granule exocytosis in NK-92 natural killer cells.

Cellular immunology - 1 Jan 2009

Pores-Fernando Arun T, Gaur Surabhi, Doyon Michelle Y, Zweifach Adam

Abstract excerpt

Cytotoxic T cells (CTLs) and natural killer cells (NKs) both kill virus-infected cells and tumor cells by releasing the cytoxic contents of their lytic granules. We recently demonstrated a role for calcineurin in lytic granule exocytosis in TALL-104 human leukemic CTLs [M.J. Grybko, J.P. Bartnik,...

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Identifiers

PMID: 18762287
DOI: 10.1016/j.cellimm.2008.07.004
PMCID: PMC2646370

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18762287-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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