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Article

Nonvesicular release of acetylcholine is required for axon targeting in the Drosophila visual system.

Proceedings of the National Academy of Sciences of the United States of America - 19 Oct 2004

Yang Hong, Kunes Sam

Abstract excerpt

We report evidence for a developmental role of acetylcholine in axon pathfinding in the Drosophila visual system. Acetylcholine was detected on photoreceptor axons during their navigation to target sites in the brain, a time well before the formation of functional synapses. The pattern of photoreceptor axon projections was severely disrupted when acetylcholine synthesis or metabolism was altered or eliminated, or...

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Identifiers

PMID: 15469930
DOI: 10.1073/pnas.0308141101
PMCID: PMC524039

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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