Article
A naturally occurring mouse model of X-linked congenital stationary night blindness.
Investigative ophthalmology & visual science - 1 Nov 1998
Pardue M T, McCall M A, LaVail M M, Gregg R G, Peachey N S
Abstract excerpt
PURPOSE: To describe a naturally occurring X-linked recessive mutation, no b-wave (nob), that compromises visual transmission between photoreceptors and second-order neurons in mice. METHODS: Affected mice were identified by recording the light-evoked response of the retina, the electroretinogram...
Topics
- Animals
- Dark Adaptation
- Disease Models, Animal
- Electroretinography
- Evoked Potentials, Visual
- Female
- Genetic Linkage
- Light
- Male
- Mice
- Mice, Inbred BALB C
- Mice, Mutant Strains
- Mutation
- Neurons
- Night Blindness
- Pedigree
- Photoreceptor Cells, Invertebrate
- Vision, Ocular