Article
Multicolor molecular beacons for allele discrimination.
Nature biotechnology - 1 Jan 1998
Tyagi S, Bratu D P, Kramer F R
Abstract excerpt
Molecular beacons are hairpin-shaped oligonucleotide probes that report the presence of specific nucleic acids in homogenous solutions. When they bind to their targets they undergo a conformational reorganization that restores the fluorescence of an internally quenched fluorophore. We found that...
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