Article
The heterogeneity of human chorionic gonadotropin (hCG). I. Characterization of peptide heterogeneity in 13 individual preparations of hCG.
Endocrinology - 1 Sept 1991
Kardana A, Elliott M M, Gawinowicz M A, Birken S, Cole L A
Abstract excerpt
Peptide variations in the alpha-subunit (molecules starting at alpha 3 and alpha 4) and beta-subunit (missing linkages at beta 44-45 and beta 47-48) of hCG have been reported by several investigators. Studies, however, have been limited to standard hCG preparations (purified from large pools of urine) and other hCG samples from mixed urines. In this study we used chromatographic procedures to purify the total hCG...
Topics
- Amino Acid Sequence
- Choriocarcinoma
- Chorionic Gonadotropin
- Chromatography, Gel
- Electrophoresis, Polyacrylamide Gel
- Female
- Genetic Variation
- Humans
- Hydatidiform Mole
- Immunoassay
- Immunoblotting