Article
The heterogeneity of human chorionic gonadotropin (hCG). II. Characteristics and origins of nicks in hCG reference standards.
Endocrinology - 1 Sept 1991
Birken S, Gawinowicz M A, Kardana A, Cole L A
Abstract excerpt
hCG, the hormone produced by the trophoblast throughout pregnancy, has peptide bond cleavages, or nicks, in the beta-subunit. We sought to compare the nature of these nicks in standard reference preparations of hCG, to determine the enzymes that may be responsible for generating the peptide bond...
Topics
- Amino Acid Sequence
- Chorionic Gonadotropin
- Chorionic Gonadotropin, beta Subunit, Human
- Chromatography, High Pressure Liquid
- Female
- Genetic Variation
- Humans
- Peptide Fragments
- Pregnancy
- Reference Standards