Article
[Learning and extinction of passive avoidance in mice with high predisposition to catalepsy].
Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova - 1 Jun 2008
Dubrovina N I, Zinov'ev D R, Zinov'eva D V, Kulikov A V
Abstract excerpt
The passive avoidance learning and extinction in mice strain ASC with high predisposition to catalepsy as compared with mice of CBA and AKR strains were analyzed. Impairment of fear extinction as a major symptom of depression was revealed in ASC mice, whereas a delay of extinction in CBA mice and fast formation of new inhibitory learning in AKR mice were found. It is suggested that the long persistence of fear in...
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