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[Effect of GDNF on the behavior of ASC mice with high hereditary predisposition to catalepsy].

Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova - 1 Jan 2000

Semenova A A, Bazovkina D B, Tsybko A S, Naumenko V S, Popova N K

Abstract excerpt

ASC mice, which were selected for high predisposition to catalepsy, are convenient genetic model for research of central mechanisms related to disorder of motor regulation. The aim of the work was to study the effect of glial cell line-derived neurotrophic factor (GDNF) on catalepsy, locomotor activity, stereotyping behavior in the marble burying test and on the dopamine level in striatum of ASC mice. It was...

Topics

Animals
Catalepsy
Corpus Striatum
Genetic Predisposition to Disease
Genotype
Glial Cell Line-Derived Neurotrophic Factor
Humans
Male
Mice
Motor Activity
Stereotyped Behavior

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25464752
DOI: 10.7868/s0044467713040102

Genes

GDNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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