Learning and extinction of a passive avoidance response in mice with high levels of predisposition to catalepsy.

doi:10.1007/s11055-009-9152-4

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Article

Learning and extinction of a passive avoidance response in mice with high levels of predisposition to catalepsy.

Neuroscience and behavioral physiology - 1 Jun 2009

Dubrovina N I, Zinov'ev D R, Zinov'eva D V, Kulikov A V

Abstract excerpt

This report presents results obtained from comparative analysis of learning and the dynamics of extinction of a conditioned passive avoidance response in ASC mice, which were bred for a high level of predisposition to catalepsy, and in CBA and AKR mice. The following findings were obtained: 1) impairments to the extinction of the memory of fear represent an important symptom of depression in ASC mice; 2)...

Topics

Animals
Avoidance Learning
Catalepsy
Depression
Extinction, Psychological
Genetic Predisposition to Disease
Male
Mice
Species Specificity

Source

Open in PubMed

Identifiers

PMID: 19430979
DOI: 10.1007/s11055-009-9152-4

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