[Il6st gene mRNA and gp130 protein distribution in the brain structures in mice differing in exagerrated freezing reaction (catalepsy)].

doi:10.7868/s0026898413030154

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Article

[Il6st gene mRNA and gp130 protein distribution in the brain structures in mice differing in exagerrated freezing reaction (catalepsy)].

Molekuliarnaia biologiia - 1 Jan 2000

Siniakova N A, Kondaurova E M, Kulikov A V, Naumchenko V S, Tikhonova M A, Popova N K

Abstract excerpt

Glycoprotein gp130 is involved in the intracellular transduction of signals from receptors ofinterleukin-6--related cytokines. The linkage between Il6st gene encoding gp130 and predisposition to excessive freezing (catalepsy) in mice was shown. The aim of present study was to investigate the Il6st mRNA concentration, the level and the rate of glycosilation of gp130 in five brain structures in catalepsy-resistant...

Topics

Animals
Brain
Catalepsy
Cytokine Receptor gp130
Freezing Reaction, Cataleptic
Gene Expression Regulation
Genetic Predisposition to Disease
Mice
Nerve Tissue Proteins
RNA, Messenger
Species Specificity

Source

Open in PubMed

Identifiers

PMID: 23888778
DOI: 10.7868/s0026898413030154

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