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Article

Knockouts of Se-glutathione peroxidase-1 and Cu,Zn superoxide dismutase exert different impacts on femoral mechanical performance of growing mice.

Molecular nutrition & food research - 1 Nov 2008

Wang Xiaodan, Gillen Elizabeth A, van der Meulen Marjolein C H, Lei Xin Gen

Abstract excerpt

The objective of this study was to determine the impact of knockout of Cu,Zn-superoxide dismutase (SOD1) and Se-glutathione peroxidase-1 (GPX1) on murine bone biomechanical properties. Femora samples were collected from wild-type (WT), SOD1-knockout [SOD1(-/-)] and GPX1-knockout [GPX1(-/-)] female mice (9-wk old, n = 7-8 per genotype) to assay for bone enzyme activities and mechanical properties in three point...

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Source

Identifiers

PMID: 18727007
DOI: 10.1002/mnfr.200700351

Genes

SOD1
GPX1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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