Article
Lateral femoral hernias in a line of FVB/NHsd mice: a new confounding lesion linked to genetic background?
Comparative medicine - 1 Aug 2008
Paquet Marilène, Penney Janice, Boerboom Derek
Abstract excerpt
Several strains of transgenic mice derived from an inbred FVB/NHsd colony developed large masses on 1 or both flanks. Although originally suspected to be a phenotypic anomaly related to genetic modifications, nontransgenic littermates subsequently were affected with equal frequency, inculpating the FVB/NHsd founder colony. The masses were subcutaneous, soft, and exophytic and appeared over the course of a few...
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