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Article

Mouse model of Sanfilippo syndrome type B: relation of phenotypic features to background strain.

Comparative medicine - 1 Dec 2003

Gografe Sylvia I, Garbuzova-Davis Svitlana, Willing Alison E, Haas Ken, Chamizo Wilfredo, Sanberg Paul R

Abstract excerpt

Sanfilippo syndrome type B or mucopolysaccharidosis type III B (MPS IIIB) is a lysosomal storage disorder that is inherited in autosomal recessive manner. It is characterized by systemic heparan sulfate accumulation in lysosomes due to deficiency of the enzyme alpha-N-acetylglucosaminidase (Naglu). Devastating clinical abnormalities with severe central nervous system involvement and somatic disease lead to...

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PMID: 14727810

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Mouse model of Sanfilippo syndrome type B: relation of phenotypic features to background strain.PMID 14727810Read ↗

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