Development of the diaphragm and genetic mouse models of diaphragmatic defects.

doi:10.1002/ajmg.c.30128

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Article

Development of the diaphragm and genetic mouse models of diaphragmatic defects.

American journal of medical genetics. Part C, Seminars in medical genetics - 15 May 2007

Ackerman Kate G, Greer John J

Abstract excerpt

Improving our understanding of diaphragmatic development is essential to making progress in defining the pathogenesis and genetic etiologies of congenital diaphragmatic defects in humans. As mouse genetic technology has given us new tools to manipulate and observe development, a number of mouse models have recently emerged that provide valuable insight to this field. In this article, we review our current...

Topics

Abdominal Muscles
Animals
COUP Transcription Factor II
DNA-Binding Proteins
Diaphragm
Disease Models, Animal
Hernia, Diaphragmatic
Humans
Lung
Mice
Mutation
Transcription Factors

Source

Open in PubMed

Identifiers

PMID: 17436296
DOI: 10.1002/ajmg.c.30128

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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