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Article

Elesclomol induces cancer cell apoptosis through oxidative stress

1 Aug 2008

Abstract excerpt

Elesclomol (formerly STA-4783) is a novel small molecule undergoing clinical evaluation in a pivotal phase III melanoma trial (SYMMETRY). In a phase II randomized, double-blinded, controlled, multi-center trial in 81 patients with stage IV metastatic melanoma, treatment with elesclomol plus paclitaxel showed a statistically significant doubling of progression-free survival time compared with treatment with...

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PMID: 18723479
DOI: 10.1158/1535-7163.mct-08-0298

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