Article
Interaction between polymorphisms of the human leukocyte antigen and HPV-16 variants on the risk of invasive cervical cancer.
BMC cancer - 22 Aug 2008
de Araujo Souza Patricia S, Maciag Paulo C, Ribeiro Karina B, Petzl-Erler Maria Luiza, Franco Eduardo L, Villa Luisa L
Abstract excerpt
BACKGROUND: Persistent infection with oncogenic types of human papillomavirus (HPV) is the major risk factor for invasive cervical cancer (ICC), and non-European variants of HPV-16 are associated with an increased risk of persistence and ICC. HLA class II polymorphisms are also associated with genetic susceptibility to ICC. Our aim is to verify if these associations are influenced by HPV-16 variability. METHODS:...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
