Article
HLA class II susceptibility to cervical cancer among Tunisian women.
Bulletin du cancer - 1 Sept 2012
Ben Othmane Yosra, Ghazouani Ezzeddine, Mezlini Amel, Lagha Awatef, Raïs Mejda, Kochkar Radhia, Zidi Sabrina, Afrit Mehdi, Mota-Vieira Luisa, Yacoubi Loueslati Besma
Abstract excerpt
The variability in host immunogenetic background, especially in human major histocompatibilty genes, has been shown to influence the susceptibility to human papillomavirus (HPV) infection and cervical neoplasia. Here, we conducted a case-control study in Tunisian women to examine the effect of genetic variation in HLA class II DRB1 and DQB1 genes on invasive cervical cancer (ICC) and squamous cell carcinoma...
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