Article
Human leukocyte antigens I and II haplotypes associated with human papillomavirus 16-positive invasive cervical cancer in Mexican women.
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society - 1 Aug 2009
Hernández-Hernández Dulce M, Cerda-Flores Ricardo M, Juárez-Cedillo Teresa, Granados-Arriola Julio, Vargas-Alarcón Gilberto, Apresa-García Teresa, Alvarado-Cabrero Isabel, García-Carrancá Alejandro, Salcedo-Vargas Mauricio, Mohar-Betancourt Alejandro
Abstract excerpt
Infection with human papillomavirus (HPV), mainly HPV type 16, is the major etiologic factor associated with cervical cancer (CC), but HPV infection alone is not sufficient for progression of precursor lesions. Host genetic susceptibility may lead to abnormal immune response resulting from virus persistence. Several studies have suggested a possible association with specific human leukocyte antigen (HLA) class I...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
