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An updated understanding of follicular lymphoma transformation

15 May 2025

Abstract excerpt

ABSTRACT: Although most patients with follicular lymphoma (FL) follow an indolent disease course, some patients experience a critical inflection point when FL transforms into an aggressive lymphoma. Historically, FL transformation is marked by poor outcomes, particularly for patients with previous FL-directed treatment. Compared with FL, transformed FL (tFL) is marked by numerous additional genetic changes,...

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Identifiers

PMID: 40373273
DOI: 10.1182/blood.2024026016

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