Article
Association of Interleukin-1 gene polymorphisms with central obesity and metabolic syndrome in a coronary heart disease population.
Human genetics - 1 Oct 2008
Carter Kim W, Hung Joseph, Powell Brenda L, Wiltshire Steven, Foo Brendan T X, Leow Yuen C, McQuillan Brendan M, Jennens Michelle, McCaskie Pamela A, Thompson Peter L, Beilby John P, Palmer Lyle J
Abstract excerpt
The objective of this study was to determine whether single nucleotide polymorphisms (SNPs) in the Interleukin-1 (IL-1) gene family are associated with central obesity and metabolic syndrome in a coronary heart disease population. The IL-1 alpha C-889T (rs1800587) and IL-1 beta +3954 (rs1143634) SNPs were studied in a Western Australian coronary heart disease (CHD) population (N = 556). Subjects who were TT...
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