Article
Identification of SNP interactions using logic regression.
Biostatistics (Oxford, England) - 1 Jan 2008
Schwender Holger, Ickstadt Katja
Abstract excerpt
Interactions of single nucleotide polymorphisms (SNPs) are assumed to be responsible for complex diseases such as sporadic breast cancer. Important goals of studies concerned with such genetic data are thus to identify combinations of SNPs that lead to a higher risk of developing a disease and to measure the importance of these interactions. There are many approaches based on classification methods such as CART...
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