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Article

Interactions between genes involved in the antioxidant defence system and breast cancer risk.

British journal of cancer - 21 Aug 2006

Oestergaard M Z, Tyrer J, Cebrian A, Shah M, Dunning A M, Ponder B A J, Easton D F, Pharoah P D P

Abstract excerpt

The aim of the study is to examine the association between multilocus genotypes across 10 genes encoding proteins in the antioxidant defence system and breast cancer. The 10 genes are SOD1, SOD2, GPX1, GPX4, GSR, CAT, TXN, TXN2, TXNRD1 and TXNRD2. In all, 2271 cases and 2280 controls were used to examine gene-gene interactions between 52 single nucleotide polymorphisms (SNPs) that are hypothesised to tag all...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 16868544
DOI: 10.1038/sj.bjc.6603272
PMCID: PMC2360671

Genes

TXNRD2
TXN
GSR
GPX4
CAT
GPX1
SOD1
SOD2
TXN2
TXNRD1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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