Article
Assessment of inhomogeneities in an E. coli physical map.
Nucleic acids research - 11 Aug 1991
Karlin S, Macken C
Abstract excerpt
A statistical method based on r-fragments, sums of distances between (r + 1) consecutive restriction enzyme sites, is introduced for detecting nonrandomness in the distribution or too markers in sequence data. The technique is applicable whenever large numbers of markers are available and will detect clumping, excessive dispersion or too much evenness of spacing of the markers. It is particularly adapted to...
Topics
- Base Sequence
- Chromosomes, Bacterial
- Chromosomes, Human, Pair 21
- Data Interpretation, Statistical
- Deoxyribonucleases, Type II Site-Specific
- Escherichia coli
- Genetic Markers
- Genetic Variation
- Humans
- Methylation
- Molecular Sequence Data