Article
An expression system to screen for inhibitors of parasite glucose transporters.
Molecular and biochemical parasitology - 1 Nov 2008
Feistel Torben, Hodson Cheryl A, Peyton David H, Landfear Scott M
Abstract excerpt
Chemotherapy of parasitic protists is limited by general toxicity, high expense and emergence of resistance to currently available drugs. Thus methods to identify new leads for further drug development are increasingly important. Previously, glucose transporters have been validated as new drug targets for protozoan parasites including Plasmodium falciparum, Leishmania mexicana and Trypanosoma brucei. A recently...
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