Article
Association of eating disorders with catechol-o-methyltransferase gene functional polymorphism.
Neuropsychobiology - 1 Jan 2006
Mikołajczyk Elzbieta, Smiarowska Małgorzata, Grzywacz Anna, Samochowiec Jerzy
Abstract excerpt
AIM: The aim of this study was to evaluate functional catechol-O-methyltransferase (COMT) genetic variation as a risk factor for eating disorders (ED). METHOD: Eighty women receiving treatment for serious ED (52 for anorexia nervosa, 28 for bulimia nervosa) and 116 age-matched females in the control group underwent COMT genotyping for polymorphism in exon 4 (codon 158). Both the low-activity allele and the...
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