Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Platelet-derived growth factor is mitogenic for O-2Aadult progenitor cells.

Glia - 1 Jan 1991

Wolswijk G, Riddle P N, Noble M

Abstract excerpt

We report that platelet-derived growth factor (PDGF) is a potent mitogen for oligodendrocyte type-2 astrocyte (O-2A) progenitor cells derived from the optic nerves of adult rats. Moreover, O-2Aadult progenitors cultured in PDGF express the range of properties we have described previously for O-2Aadult progenitors cultured in the presence of type-1 astrocytes. Similarly, previous studies have demonstrated that...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antibodies
Share to Antibodies, Monoclonal
Share to Cell Division

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cell Movement

Share to Culture Media

Share to Phenotype

Share to Stem Cells

Share to Time Factors

Source

Identifiers

PMID: 1834566
DOI: 10.1002/glia.440040509

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Platelet-derived growth factor is mitogenic for O-2Aadult progenitor cells.PMID 1834566Read ↗

CG-4, a new bipotential glial cell line from rat brain, is capable of differentiating in vitro into either mature oligodendrocytes or type-2 astrocytes.Semantic proximity Read ↗

Glial cell mitogens bFGF and PDGF differentially regulate development of O4+GalC- oligodendrocyte progenitors.Semantic proximity Read ↗

O-2A glial progenitors from mature brain respond to CNS neuronal cell line-derived growth factors.Semantic proximity Read ↗

NG2 Cells in White Matter But Not Gray Matter Proliferate in Response to PDGFSemantic proximity Read ↗

Immature neurons from CNS stem cells proliferate in response to platelet-derived growth factor.Semantic proximity Read ↗

Growth and differentiation properties of O-2A progenitors purified from rat cerebral hemispheres.Semantic proximity Read ↗

Human oligodendrocyte precursor cells in vitro: phenotypic analysis and differential response to growth factors.Semantic proximity Read ↗

Autocrine inhibition of mitotic activity in cultured oligodendrocyte-type-2 astrocyte (O-2A) precursor cells.Semantic proximity Read ↗

FGF-2 converts mature oligodendrocytes to a novel phenotype.Semantic proximity Read ↗

NG2-positive cells generate A2B5-positive oligodendrocyte precursor cells.Semantic proximity Read ↗

Cerebral white matter contains PDGF-responsive precursors to O2A cells.Semantic proximity Read ↗

Bone Morphogenetic Proteins Induce Astroglial Differentiation of Oligodendroglial–Astroglial Progenitor CellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.