Article
Cerebral white matter contains PDGF-responsive precursors to O2A cells.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 1 Jun 1990
Grinspan J B, Stern J L, Pustilnik S M, Pleasure D
Abstract excerpt
Cells dissociated from the cerebral white matter of immature rats were maintained in monolayer culture. Treatment with platelet-derived growth factor (PDGF) caused a large increase in the numbers of "O2A" oligodendroglial precursor cells (which bind the monoclonal antibody A2B5) and subsequently in the numbers of galactocerebroside (galC)-positive oligodendroglia. A2B5-negative "pre-O2A cells" in cerebral white...
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