Article
Cerebral white matter contains PDGF-responsive precursors to O2A cells.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 1 Jun 1990
Grinspan J B, Stern J L, Pustilnik S M, Pleasure D
Abstract excerpt
Cells dissociated from the cerebral white matter of immature rats were maintained in monolayer culture. Treatment with platelet-derived growth factor (PDGF) caused a large increase in the numbers of "O2A" oligodendroglial precursor cells (which bind the monoclonal antibody A2B5) and subsequently...
Topics
- Animals
- Astrocytes
- Blood
- Brain
- Cell Line
- Mitogens
- Oligodendroglia
- Phenotype
- Platelet-Derived Growth Factor
- Rats
- Rats, Inbred Strains
- Recruitment, Neurophysiological
- Stem Cells
- Vimentin